Proteomic Response of <i>Paracoccidioides brasiliensis</i> Exposed to the Antifungal 4-Methoxynaphthalene-N-acylhydrazone Reveals Alteration in Metabolism

Proteomic Response of <i>Paracoccidioides brasiliensis</i> Exposed to the Antifungal 4-Methoxynaphthalene-N-acylhydrazone Reveals Alteration in Metabolism

<b>Background:</b> Paracoccidioidomycosis is a neglected mycosis with a high socioeconomic impact that requires long-term treatment with antifungals that have limitations in their use. The development of antifungals targeting essential proteins that are present exclusively in the fungus...

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Bibliographic Details
Main Authors: Lívia do Carmo Silva, Kleber Santiago Freitas e Silva, Olívia Basso Rocha, Katheryne Lohany Barros Barbosa, Andrew Matheus Frederico Rozada, Gisele de Freitas Gauze, Célia Maria de Almeida Soares, Maristela Pereira
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Journal of Fungi
Subjects:
paracoccidioidomycosis
<i>N</i>-acylhydrazone
antifungal
proteome
Online Access:https://www.mdpi.com/2309-608X/9/1/66

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https://www.mdpi.com/2309-608X/9/1/66

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