Appraising associations between signature lipidomic biomarkers and digestive system cancer risk: novel evidences from a prospective cohort study of UK Biobank and Mendelian randomization analyses

Appraising associations between signature lipidomic biomarkers and digestive system cancer risk: novel evidences from a prospective cohort study of UK Biobank and Mendelian randomization analyses

Abstract Background The roles of serum lipids on digestive system cancer (DSC) risk were still inconclusive. In this study, we systematically assessed indicative effects of signature lipidomic biomarkers (high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and...

Full description

Bibliographic Details
Main Authors: Yuanlin Sun, Donghui Cao, Yang Zhang, Yanhua Wu, Zhifang Jia, Yingnan Cui, Dongming Li, Xueyuan Cao, Jing Jiang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Lipids in Health and Disease
Subjects:
Signature lipidomic biomarkers
Digestive system cancer risk
Polygenic risk score
Linear and nonlinear Mendelian randomization analysis
Phenotypic associations
Causal associations
Online Access:https://doi.org/10.1186/s12944-024-02053-9

Internet

https://doi.org/10.1186/s12944-024-02053-9

Similar Items