Mitochondrial DNA quantification correlates with the developmental potential of human euploid blastocysts but not with that of mosaic blastocysts

Mitochondrial DNA quantification correlates with the developmental potential of human euploid blastocysts but not with that of mosaic blastocysts

Abstract Purpose We aimed to study the association between adjusted mtDNA levels in human trophectoderm biopsy samples and the developmental potential of euploid and mosaic blastocysts. Methods We analyzed relative mtDNA levels in 2,814 blastocysts obtained from 576 couples undergoing preimplantatio...

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Bibliographic Details
Main Authors: Wen Luo, Yi-Min Zheng, Yan Hao, Ying Zhang, Ping Zhou, Zhaolian Wei, Yunxia Cao, Dawei Chen
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Pregnancy and Childbirth
Subjects:
Mitochondrion
Mitochondrial genome
mtDNA quantification
Blastocyst
Embryo viability
Preimplantation genetic testing
Online Access:https://doi.org/10.1186/s12884-023-05760-w

Internet

https://doi.org/10.1186/s12884-023-05760-w

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