Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti

Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti

Aedes aegypti can act as a vector for viral pathogens but the mechanism of viral resistance and evolving host-pathogen tolerance are poorly understood. Here the authors structurally characterise a duplicated pair of interacting Toll immunoreceptors and the cytokine ligand Spaetzle1C and show their d...

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Bibliographic Details
Main Authors: Yoann Saucereau, Thomas H. Wilson, Matthew C. K. Tang, Martin C. Moncrieffe, Steven W. Hardwick, Dimitri Y. Chirgadze, Sandro G. Soares, Maria Jose Marcaida, Nicholas J. Gay, Monique Gangloff
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32690-6

Internet

https://doi.org/10.1038/s41467-022-32690-6

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