Synthesis and Crystal Structure of Benzyl [(1S)-1-(5-amino-1,3,4-oxadiazol-2-yl)-2-phenylethyl]carbamate

Synthesis and Crystal Structure of Benzyl [(1S)-1-(5-amino-1,3,4-oxadiazol-2-yl)-2-phenylethyl]carbamate

The conversion of Z-phenylalanine hydrazide with cyanogen bromide resulted in the formation of the corresponding 2-amino-1,3,4-oxadiazole by spontaneous cyclization of the intermediary cyanohydrazide. The molecular structure of the product was confirmed by single crystal X-ray diffraction. Crystals...

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Bibliographic Details
Main Authors: Reik Löser, Martin Nieger, Michael Gütschow
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Crystals
Subjects:
1,3,4-oxadiazoles
cyanohydrazides
hydrogen bonds
edge-to-face interactions
Online Access:http://www.mdpi.com/2073-4352/2/3/1201

Internet

http://www.mdpi.com/2073-4352/2/3/1201

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