The Expression and Prognostic Value of SUMO1-Activating Enzyme Subunit 1 and Its Potential Mechanism in Triple-Negative Breast Cancer

The Expression and Prognostic Value of SUMO1-Activating Enzyme Subunit 1 and Its Potential Mechanism in Triple-Negative Breast Cancer

Background: Triple-negative breast cancer (TNBC) is the most invasive and metastatic subtype of breast cancer. SUMO1-activating enzyme subunit 1 (SAE1), an E1-activating enzyme, is indispensable for protein SUMOylation. SAE1 has been found to be a relevant biomarker for progression and prognosis in...

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Bibliographic Details
Main Authors: Qingshui Wang, Wenting Zhong, Lin Deng, Qili Lin, Youyu Lin, Hongxia Liu, Luyun Xu, Lingfang Lu, Yajuan Chen, Jianping Huang, Meichen Jiang, Han Xiao, Jie Zhang, He Li, Yuxiang Lin, Chuangui Song, Yao Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
TNBC
SAE1
WGCNA
prognosis
cell cycle
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.729211/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.729211/full

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