A Single High Dose of Flufenamic Acid in Rats does not Reduce the Damage Associated with the Rat Lithium-Pilocarpine Model of Status Epilepticus but Leads to Deleterious Outcomes

A Single High Dose of Flufenamic Acid in Rats does not Reduce the Damage Associated with the Rat Lithium-Pilocarpine Model of Status Epilepticus but Leads to Deleterious Outcomes

Background: Epilepsy is one of the most common neurologic diseases, and around 30% of all epilepsies, particularly the temporal lobe epilepsy (TLE), are highly refractory to current pharmacological treatments. Abnormal synchronic neuronal activity, brain glucose metabolism alterations, neurodegenera...

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Bibliographic Details
Main Authors: Nira Hernández-Martín, Francisca Gomez, Ágata Silván, Rubén Fernández de la Rosa, Mercedes Delgado, Pablo Bascuñana, Miguel Ángel Pozo, Luis García-García
Format: Article
Language:English
Published: IMR Press 2023-05-01
Series:Journal of Integrative Neuroscience
Subjects:
epilepsy
flufenamic acid
neuroinflammation
pet
epileptogenesis
fdg
Online Access:https://www.imrpress.com/journal/JIN/22/3/10.31083/j.jin2203075

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https://www.imrpress.com/journal/JIN/22/3/10.31083/j.jin2203075

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