Feedback inhibition of L1 and alu retrotransposition through altered double strand break repair kinetics

<p>Abstract</p> <p>Background</p> <p>Cells adapt to various chronic toxic exposures in a multitude of ways to minimize further damage and maximize their growth potential. Expression of L1 elements in the human genome can be greatly deleterious to cells, generating numer...

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Bibliographic Details
Main Authors: Wallace Nicholas A, Belancio Victoria P, Faber Zach, Deininger Prescott
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Mobile DNA
Online Access:http://www.mobilednajournal.com/content/1/1/22