Double-jeopardy: scRNA-seq doublet/multiplet detection using multi-omic profiling
Summary: The computational detection and exclusion of cellular doublets and/or multiplets is a cornerstone for the identification the true biological signals from single-cell RNA sequencing (scRNA-seq) data. Current methods do not sensitively identify both heterotypic and homotypic doublets and/or m...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-05-01
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Series: | Cell Reports: Methods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667237521000084 |