Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart failure by secreting PDGF-BB

Abstract Recent studies have suggested that transplant of hiPS-CMs is a promising approach for treating heart failure. However, the optimally clinical benefits have been hampered by the immature nature of the hiPS-CMs, and the hiPS-CMs-secreted proteins contributing to the repair of cardiomyocytes r...

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Bibliographic Details
Main Authors: Hongmei Li, Fenfang Wu, Guangrui Huang, Di Wu, Ting Wang, Xiashuang Wang, Kai Wang, Yuyin Feng, Anlong Xu
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-01045-4