Biology before the SOS Response—DNA Damage Mechanisms at Chromosome Fragile Sites
The <i>Escherichia coli</i> SOS response to DNA damage, discovered and conceptualized by Evelyn Witkin and Miroslav Radman, is the prototypic DNA-damage stress response that upregulates proteins of DNA protection and repair, a radical idea when formulated in the late 1960s and early 1970...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
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Series: | Cells |
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Online Access: | https://www.mdpi.com/2073-4409/10/9/2275 |