The Power of Malaria Vaccine Trials Using Controlled Human Malaria Infection.
Controlled human malaria infection (CHMI) in healthy human volunteers is an important and powerful tool in clinical malaria vaccine development. However, power calculations are essential to obtain meaningful estimates of protective efficacy, while minimizing the risk of adverse events. To optimize p...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC5230743?pdf=render |