NXN Gene Epigenetic Changes in an Adult Neurogenesis Model of Alzheimer’s Disease

NXN Gene Epigenetic Changes in an Adult Neurogenesis Model of Alzheimer’s Disease

In view of the proven link between adult hippocampal neurogenesis (AHN) and learning and memory impairment, we generated a straightforward adult neurogenesis <i>in vitro</i> model to recapitulate DNA methylation marks in the context of Alzheimer’s disease (AD). Neural progenitor cells (N...

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Bibliographic Details
Main Authors: Idoia Blanco-Luquin, Blanca Acha, Amaya Urdánoz-Casado, Eva Gómez-Orte, Miren Roldan, Diego R. Pérez-Rodríguez, Juan Cabello, Maite Mendioroz
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
adult hippocampal neurogenesis
NPCs
Alzheimer’s disease
Aβ peptide
DNA methylation
gene expression
Online Access:https://www.mdpi.com/2073-4409/11/7/1069

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https://www.mdpi.com/2073-4409/11/7/1069

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