An Injectable Click-Crosslinked Hydrogel that Prolongs Dexamethasone Release from Dexamethasone-Loaded Microspheres

An Injectable Click-Crosslinked Hydrogel that Prolongs Dexamethasone Release from Dexamethasone-Loaded Microspheres

Our purpose was to test whether a preparation of injectable formulations of dexamethasone (Dex)-loaded microspheres (Dex-Ms) mixed with click-crosslinked hyaluronic acid (Cx-HA) (or Pluronic (PH) for comparison) prolongs therapeutic levels of released Dex. Dex-Ms were prepared using a monoaxial-nozz...

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Bibliographic Details
Main Authors: Ji Yeon Heo, Jung Hyun Noh, Seung Hun Park, Yun Bae Ji, Hyeon Jin Ju, Da Yeon Kim, Bong Lee, Moon Suk Kim
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Pharmaceutics
Subjects:
injectable hydrogel
depot
click-reaction
microsphere
retardation
Online Access:https://www.mdpi.com/1999-4923/11/9/438

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https://www.mdpi.com/1999-4923/11/9/438

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