LKB1 and Notch Pathways Interact and Control Biliary Morphogenesis.

LKB1 and Notch Pathways Interact and Control Biliary Morphogenesis.

LKB1 is an evolutionary conserved kinase implicated in a wide range of cellular functions including inhibition of cell proliferation, regulation of cell polarity and metabolism. When Lkb1 is inactivated in the liver, glucose homeostasis is perturbed, cellular polarity is affected and cholestasis dev...

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Bibliographic Details
Main Authors: Pierre-Alexandre Just, Alexis Poncy, Sara Charawi, Rajae Dahmani, Massiré Traore, Typhanie Dumontet, Valérie Drouet, Florent Dumont, Hélène Gilgenkrantz, Sabine Colnot, Benoit Terris, Cédric Coulouarn, Frédéric Lemaigre, Christine Perret
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4687046?pdf=render

Internet

http://europepmc.org/articles/PMC4687046?pdf=render

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