Preclinical assessment of intravitreal ramucirumab: in vitro and in vivo safety profile

Abstract Background Anti-angiogenic drugs remain the mainstay therapy for several vascular retinal pathologies. The repurposing of approved anti-angiogenic drugs for use in ophthalmology can increase therapeutic options and reduce costs. The purpose of this study was to investigate the ocular safety...

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Main Authors: Jarbas Emílio de Moraes Neto, Felipe Pereira, Raquel Leão Neves, Nilana Meza Tenório de Barros, Cristiane Damas Gil, Arthur Gustavo Fernandes, Sung Eun Song Watanabe, Carsten Helmut Meyer, Michel Eid Farah, Eduardo Buchele Rodrigues
Format: Article
Language:English
Published: BMC 2020-09-01
Series:International Journal of Retina and Vitreous
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40942-020-00243-y