Susceptibility and Severity of COVID-19 Are Both Associated With Lower Overall Viral–Peptide Binding Repertoire of HLA Class I Molecules, Especially in Younger People

Susceptibility and Severity of COVID-19 Are Both Associated With Lower Overall Viral–Peptide Binding Repertoire of HLA Class I Molecules, Especially in Younger People

An important number of studies have been conducted on the potential association between human leukocyte antigen (HLA) genes and COVID-19 susceptibility and severity since the beginning of the pandemic. However, case–control and peptide-binding prediction methods tended to provide inconsistent conclu...

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Bibliographic Details
Main Authors: Hamid Reza Ghasemi Basir, Mohammad Mahdi Majzoobi, Samaneh Ebrahimi, Mina Noroozbeygi, Seyed Hamid Hashemi, Fariba Keramat, Mojgan Mamani, Peyman Eini, Saeed Alizadeh, Ghasem Solgi, Da Di
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
COVID-19
HLA
overall binding repertoire
SARS-CoV-2-derived peptides
HLA binding prediction
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.891816/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.891816/full

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