The capsaicin receptor TRPV1 is the first line defense protecting from acute non damaging heat: a translational approach

The capsaicin receptor TRPV1 is the first line defense protecting from acute non damaging heat: a translational approach

Abstract Background Pain is the vital sense preventing tissue damage by harmful noxious stimuli. The capsaicin receptor TRPV1 is activated by noxious temperatures, however, acute heat pain is only marginally affected in mice after TRPV1 knockout but completely eliminated in mice lacking TRPV1 positi...

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Bibliographic Details
Main Authors: Daniela C. Rosenberger, Uta Binzen, Rolf-Detlef Treede, Wolfgang Greffrath
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Translational Medicine
Subjects:
Near infrared laser
Heat pain
Nociception
Desensitization
Primary sensory neurons
Online Access:https://doi.org/10.1186/s12967-019-02200-2

Internet

https://doi.org/10.1186/s12967-019-02200-2

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