Longitudinal improvements in clinical and functional outcomes following initiation of elexacaftor/tezacaftor/ivacaftor in patients with cystic fibrosis

Longitudinal improvements in clinical and functional outcomes following initiation of elexacaftor/tezacaftor/ivacaftor in patients with cystic fibrosis

Background: Use of elexacaftor/tezacaftor/ivacaftor (ETI) for treatment of cystic fibrosis (CF) has resulted in unprecedented clinical improvements necessitating development of outcome measures for monitoring disease course. Intranasal micro-optical coherence tomography (μOCT) has previously helped...

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Bibliographic Details
Main Authors: Kadambari Vijaykumar, Hui Min Leung, Amilcar Barrios, Justin Wade, Heather Y. Hathorne, David P. Nichols, Guillermo J. Tearney, Steven M. Rowe, George M. Solomon
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
Cystic fibrosis
Highly effective modulator therapies
Micro-optical coherence tomography
Mucociliary abnormalities
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024052198

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http://www.sciencedirect.com/science/article/pii/S2405844024052198

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