Nuclear transport maintenance of USP22-AR by Importin-7 promotes breast cancer progression

Abstract The translocation of biological macromolecules between cytoplasm and nucleus is of great significance to maintain various life processes in both normal and cancer cells. Disturbance of transport function likely leads to an unbalanced state between tumor suppressors and tumor-promoting facto...

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Bibliographic Details
Main Authors: Geng-Xi Cai, Wei-Yao Kong, Yuan Liu, Shu-Yi Zhong, Qing Liu, Yuan-Fei Deng, Guo-Lin Ye
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01525-8