The minichromosome maintenance complex drives esophageal basal zone hyperplasia

The minichromosome maintenance complex drives esophageal basal zone hyperplasia

Eosinophilic esophagitis (EoE) is a chronic gastrointestinal disorder characterized by food antigen–driven eosinophilic inflammation and hyperproliferation of esophageal mucosa. By utilizing a large-scale, proteomic screen of esophageal biopsies, we aimed to uncover molecular drivers of the disease....

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Bibliographic Details
Main Authors: Mark Rochman, Yrina Rochman, Julie M. Caldwell, Lydia E. Mack, John A. Besse, Nathan P. Manes, Sung Hwan Yoon, Tetsuo Shoda, Aleksandra Nita-Lazar, Marc E. Rothenberg
Format: Article
Language:English
Published: American Society for Clinical investigation 2023-09-01
Series:JCI Insight
Subjects:
Gastroenterology
Immunology
Online Access:https://doi.org/10.1172/jci.insight.172143

Internet

https://doi.org/10.1172/jci.insight.172143

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