BATF and BATF3 deficiency alters CD8+ effector/exhausted T cells balance in skin transplantation

BATF and BATF3 deficiency alters CD8+ effector/exhausted T cells balance in skin transplantation

Abstract Background It is well-established that CD8+ T-cells play a critical role in graft rejection. The basic leucine zipper ATF-like transcription factor (BATF) and BATF3 are transcriptional factors expressed in T lymphocytes. Herein, we investigated the functions of BATF and BATF3 in the differe...

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Bibliographic Details
Main Authors: Chenghao Li, Zongtao Liu, Zihao Wang, Wai Yen Yim, Yajun Huang, Yuqi Chen
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Molecular Medicine
Subjects:
CD8+ T-cells
transcription factors
BATF
Graft rejection
Online Access:https://doi.org/10.1186/s10020-024-00792-0

Internet

https://doi.org/10.1186/s10020-024-00792-0

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