Interferon-tau protects bovine endometrial epithelial cells against inflammatory injury by regulating the PI3K/AKT/β-catenin/FoxO1 signaling axis

Interferon-tau protects bovine endometrial epithelial cells against inflammatory injury by regulating the PI3K/AKT/β-catenin/FoxO1 signaling axis

ABSTRACT: Endometritis is one of the most common causes of infertility in dairy cows, and is histopathologically characterized by inflammation and damage of endometrial epithelium. Interferon-tau (IFN-τ) is a novel type I interferon secreted by ruminant trophoblast cells with low cytotoxicity even a...

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Bibliographic Details
Main Authors: Kangfeng Jiang, Jinyin Cai, Qianming Jiang, Juan J. Loor, Ganzhen Deng, Xiaobing Li, Jing Yang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Dairy Science
Subjects:
dairy cow
endometritis
interferon-tau
cell injury
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030223020234

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http://www.sciencedirect.com/science/article/pii/S0022030223020234

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