Observed intervention effects for mortality in randomised clinical trials: a methodological study protocol

Introduction It is essential to choose a realistic anticipated intervention effect when calculating a sample size for a randomised clinical trial. Unfortunately, anticipated intervention effects are often inflated, when compared with the ‘true’ intervention effects. This is documented for mortality...

Full description

Bibliographic Details
Main Authors: Janus Christian Jakobsen, Christian Gluud, Lehana Thabane, Lawrence Mbuagbaw, Ole Mathiesen, Eliana Rulli, Elena Biagioli, Caroline Kamp Jørgensen, Mathias Lühr Hansen, Maria Chiaruttini
Format: Article
Language:English
Published: BMJ Publishing Group 2023-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/6/e072550.full