Focal adhesion-mediated directional cell migration guided by gradient-stretched substrate

Summary: Soft tissues experience strain under mechanical stresses, storing energy as residual stresses and strain energy. However, the specific impact of such strain on cell migration and its molecular mechanisms remains unclear. In this study, we investigated this by using polydimethylsiloxane (PDM...

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Bibliographic Details
Main Authors: Zijia Chen, Xiaoning Han, Bo Che, Huiping Feng, Yue Zhou, Linhong Deng, Xiang Wang
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224016717