Cellular crosstalk of macrophages and therapeutic implications in non-small cell lung cancer revealed by integrative inference of single-cell transcriptomics

Cellular crosstalk of macrophages and therapeutic implications in non-small cell lung cancer revealed by integrative inference of single-cell transcriptomics

Introduction: Non-small cell lung cancer (NSCLC) exhibits heterogeneity with diverse immune cell infiltration patterns that can influence tumor cell behavior and immunotherapy. A comprehensive characterization of the tumor microenvironment can guide precision medicine.Methods: Here, we generated a s...

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Bibliographic Details
Main Authors: Lei Wu, Wenying Xia, Yiting Hua, Kun Fan, Yanfei Lu, Min Wang, Yuexinzi Jin, Wei Zhang, Shiyang Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
NSCLC
scRNA-seq
tumor-associated macrophages
cellular crosstalk
therapeutic implications
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1295442/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1295442/full

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