Computational protein design approaches with significant biological outcomes: progress and challenges
Enzymes are powerful biocatalysts, however, so far there is still a large gap between the number of enzyme-based practical applications and that of naturally occurring enzymes. Multiple experimental approaches have been applied to generate nearly all possible mutations of target enzymes, allowing th...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-09-01
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Series: | Computational and Structural Biotechnology Journal |
Online Access: | http://journals.sfu.ca/rncsb/index.php/csbj/article/view/csbj.201209007 |