Histone acetyltransferase Gcn5-mediated histone H3 acetylation facilitates cryptococcal morphogenesis and sexual reproduction

Histone acetyltransferase Gcn5-mediated histone H3 acetylation facilitates cryptococcal morphogenesis and sexual reproduction

ABSTRACT Sexual reproduction is the primary driving force behind eukaryotic environmental adaptation and evolution. In the human fungal pathogen Cryptococcus neoformans, sexual reproduction plays a critical role in the emergence of highly virulent strains and drug-resistant variants. The sexual life...

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Bibliographic Details
Main Authors: Man Chen, Yuanli Liu, Zhuozhuo Liu, Lin Su, Lili Yan, Yuan Huang, Ye Huang, Wei Zhang, Xinping Xu, Fanglin Zheng
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mSphere
Subjects:
Cryptococcus neoformans
morphogenesis
sexual reproduction
histone acetylation
Gcn5
Online Access:https://journals.asm.org/doi/10.1128/msphere.00299-23

Internet

https://journals.asm.org/doi/10.1128/msphere.00299-23

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