STING in tumors: a focus on non-innate immune pathways

Cyclic GMP-AMP synthase (cGAS) and downstream stimulator of interferon genes (STING) are involved in mediating innate immunity by promoting the release of interferon and other inflammatory factors. Mitochondrial DNA (mtDNA) with a double-stranded structure has greater efficiency and sensitivity in b...

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Bibliographic Details
Main Authors: Jiaying Yang, Mei Yang, Yingtong Wang, Jicheng Sun, Yiran Liu, Ling Zhang, Baofeng Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1278461/full