Behavioral characterization in MPTP/p mouse model of Parkinson’s disease

We evaluated the practicability of using the rarely utilized C57BL/6N mouse as a Parkinson’s disease model established via the acute MPTP/probenecid (MPTP/p) protocol. We confirmed dopaminergic degeneration in terms of decreased expression levels of tyrosine hydroxylase in the substantia nigra a...

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Bibliographic Details
Main Authors: Mai Wada, Mary Jasmin Ang, Poornima D. E. Weerasinghe-Mudiyanselage, Sung-Ho Kim, Jong-Choon Kim, Taekyun Shin, Changjong Moon
Format: Article
Language:English
Published: IMR Press 2021-06-01
Series:Journal of Integrative Neuroscience
Subjects:
Online Access:https://jin.imrpress.com/fileup/1757-448X/PDF/1625014728953-1784839714.pdf