Angiotensin type 1 receptor mediates renal production and conversion of prostaglandins E to Fα in conscious diabetic rats
Introduction: Previous studies demonstrated that stimulation of angiotensin subtype 1 receptor (AT 1 R) led to increased renal generation of prostaglandins E 2 (PGE 2 ) and renal inflammation. In turn, PGE 2 increases AT 1 R activity. The conversion of PGE 2 to the less active metabolite prostagland...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publications
2015-12-01
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| Series: | Journal of the Renin-Angiotensin-Aldosterone System |
| Online Access: | https://doi.org/10.1177/1470320315592566 |