Adipocyte P2Y14 receptors play a key role in regulating whole-body glucose and lipid homeostasis

Adipocyte P2Y14 receptors play a key role in regulating whole-body glucose and lipid homeostasis

Obesity is the major driver of the worldwide epidemic in type 2 diabetes (T2D). In the obese state, chronically elevated plasma free fatty acid levels contribute to peripheral insulin resistance, which can ultimately lead to the development of T2D. For this reason, drugs that are able to regulate li...

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Bibliographic Details
Main Authors: Shanu Jain, Sai P. Pydi, Young-Hwan Jung, Mirko Scortichini, Efrat L. Kesner, Tadeusz P. Karcz, Donald N. Cook, Oksana Gavrilova, Jürgen Wess, Kenneth A. Jacobson
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-05-01
Series:JCI Insight
Subjects:
Metabolism
Online Access:https://doi.org/10.1172/jci.insight.146577

Internet

https://doi.org/10.1172/jci.insight.146577

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