Modeling grey matter atrophy as a function of time, aging or cognitive decline show different anatomical patterns in Alzheimer's disease

Background: Grey matter (GM) atrophy in Alzheimer's disease (AD) is most commonly modeled as a function of time. However, this approach does not take into account inter-individual differences in initial disease severity or changes due to aging. Here, we modeled GM atrophy within individuals acr...

Full description

Bibliographic Details
Main Authors: Ellen Dicks, Lisa Vermunt, Wiesje M. van der Flier, Pieter Jelle Visser, Frederik Barkhof, Philip Scheltens, Betty M. Tijms
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158219301366