Regulation of mesenchymal stromal cells through fine tuning of canonical Wnt signaling

Mesenchymal stromal cells (MSCs) have been extensively utilized for various cell therapeutic trials, but the signals regulating their stromal function remain largely unclear. Here, we show that canonical Wnt signals distinctively regulate MSCs in a biphasic manner depending on signal intensity, i.e....

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Bibliographic Details
Main Authors: Jin-A Kim, Hyun-Kyung Choi, Tae-Min Kim, Sun-Hee Leem, Il-Hoan Oh
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506115000409