Multiplexed Genome Editing for Efficient Phenotypic Screening in Zebrafish

Zebrafish are widely used to investigate candidate genes for human diseases. While the emergence of CRISPR-Cas9 technology has revolutionized gene editing, the use of individual guide RNAs limits the efficiency and application of this technology in functional genetics research. Multiplexed genome ed...

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Bibliographic Details
Main Authors: Shuyu Guo, Ge Gao, Cuizhen Zhang, Gang Peng
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Veterinary Sciences
Subjects:
Online Access:https://www.mdpi.com/2306-7381/9/2/92