Capsaicin and Piperine Can Overcome Multidrug Resistance in Cancer Cells to Doxorubicin

Background: Multidrug resistance (MDR) can develop in cancer cells after treatment with anticancer drugs, mainly due to the overexpression of the ATP-binding cassette (ABC) transporters. We analyzed the ability of two pungent-tasting alkaloids—capsaicin and piperine from Capsicum frutescens and Pipe...

Full description

Bibliographic Details
Main Authors: Hanmei Li, Sonja Krstin, Shihui Wang, Michael Wink
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/3/557