IFN-γ derived from activated human CD4+ T cells inhibits the replication of SARS-CoV-2 depending on cell-type and viral strain

IFN-γ derived from activated human CD4+ T cells inhibits the replication of SARS-CoV-2 depending on cell-type and viral strain

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and vaccination elicit both T cell and B cell immune responses in immunocompetent individuals. However, the mechanisms underlying the antiviral effects mediated by CD4+ T cells are not fully understood. In this study, we...

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Bibliographic Details
Main Authors: Jun Shimizu, Tadahiro Sasaki, Guang Han Ong, Ritsuko Koketsu, Yoshihiro Samune, Emi E. Nakayama, Tetsuharu Nagamoto, Yuki Yamamoto, Kazuo Miyazaki, Tatsuo Shioda
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-77969-4

Internet

https://doi.org/10.1038/s41598-024-77969-4

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