Statins and cognitive decline in patients with Alzheimer’s and mixed dementia: a longitudinal registry-based cohort study

Statins and cognitive decline in patients with Alzheimer’s and mixed dementia: a longitudinal registry-based cohort study

Abstract Background Disturbances in brain cholesterol homeostasis may be involved in the pathogenesis of Alzheimer’s disease (AD). Lipid-lowering medications could interfere with neurodegenerative processes in AD through cholesterol metabolism or other mechanisms. Objective To explore the associatio...

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Main Authors: Bojana Petek, Henrike Häbel, Hong Xu, Marta Villa-Lopez, Irena Kalar, Minh Tuan Hoang, Silvia Maioli, Joana B. Pereira, Shayan Mostafaei, Bengt Winblad, Milica Gregoric Kramberger, Maria Eriksdotter, Sara Garcia-Ptacek
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Alzheimer’s Research & Therapy
Subjects:
Cohort study
Statins
HMG-CoA reductase inhibitors
Alzheimer's disease
Cognitive impairment
Cholesterol metabolism
Online Access:https://doi.org/10.1186/s13195-023-01360-0

Internet

https://doi.org/10.1186/s13195-023-01360-0

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