Contribution of mTOR and PTEN to Radioresistance in Sporadic and NF2-Associated Vestibular Schwannomas: A Microarray and Pathway Analysis

Contribution of mTOR and PTEN to Radioresistance in Sporadic and NF2-Associated Vestibular Schwannomas: A Microarray and Pathway Analysis

The use of radiation treatment has increased for both sporadic and neurofibromatosis type 2 (NF2)-associated vestibular schwannoma (VS). However, there are a subset of radioresistant tumors and systemic treatments that are seldom used in these patients. We investigated molecular alterations after ra...

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Bibliographic Details
Main Authors: Isabel Gugel, Florian H. Ebner, Florian Grimm, Stefan Czemmel, Frank Paulsen, Christian Hagel, Marcos Tatagiba, Sven Nahnsen, Ghazaleh Tabatabai
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
neurofibromatosis type 2
microarray analysis
radioresistance
signaling
vestibular schwannoma
Online Access:https://www.mdpi.com/2072-6694/12/1/177

Internet

https://www.mdpi.com/2072-6694/12/1/177

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