Effects of Human RelA Transgene on Murine Macrophage Inflammatory Responses

Effects of Human RelA Transgene on Murine Macrophage Inflammatory Responses

The NFκB transcription factors are major regulators of innate immune responses, and NFκB signal pathway dysregulation is linked to inflammatory disease. Here, we utilised bone marrow-derived macrophages from the p65-DsRedxp/IκBα-eGFP transgenic strain to study the functional implication of xenogenei...

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Bibliographic Details
Main Authors: Stamatia Papoutsopoulou, Lorna Morris, Andrew Bayliff, Thomas Mair, Hazel England, Massimiliano Stagi, François Bergey, Mohammad Tauqeer Alam, Raheleh Sheibani-Tezerji, Philip Rosenstiel, Werner Müller, Vitor A. P. Martins Dos Santos, Barry J. Campbell
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomedicines
Subjects:
macrophage
NFκB
RelA(p65)
inflammation
lipid A
lipopolysaccharide
Online Access:https://www.mdpi.com/2227-9059/10/4/757

Internet

https://www.mdpi.com/2227-9059/10/4/757

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