TCR Sequencing in Mouse Models of Allorecognition Unveils the Features of Directly and Indirectly Activated Clonotypes

TCR Sequencing in Mouse Models of Allorecognition Unveils the Features of Directly and Indirectly Activated Clonotypes

Allorecognition is known to involve a large number of lymphocytes carrying diverse T-cell receptor repertoire. Thus, one way to understand allorecognition and rejection mechanisms is via high-throughput sequencing of T-cell receptors. In this study, in order to explore and systematize the properties...

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Bibliographic Details
Main Authors: Valeriy Tereshchenko, Daniil Shevyrev, Marina Fisher, Aleksei Bulygin, Julia Khantakova, Sergey Sennikov
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
allorecognition
alloreactivity
transplantation
direct pathway
indirect pathway
TCR sequencing
Online Access:https://www.mdpi.com/1422-0067/24/15/12075

Internet

https://www.mdpi.com/1422-0067/24/15/12075

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