Circulating Tumor DNA Profiling in Liver Transplant for Hepatocellular Carcinoma, Cholangiocarcinoma, and Colorectal Liver Metastases: A Programmatic Proof of Concept

Circulating Tumor DNA Profiling in Liver Transplant for Hepatocellular Carcinoma, Cholangiocarcinoma, and Colorectal Liver Metastases: A Programmatic Proof of Concept

Introduction: Circulating tumor DNA (ctDNA) is emerging as a promising, non-invasive diagnostic and surveillance biomarker in solid organ malignancy. However, its utility before and after liver transplant (LT) for patients with primary and secondary liver cancers is still underexplored. Methods: Pat...

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Bibliographic Details
Main Authors: Hanna Hong, Chase J. Wehrle, Mingyi Zhang, Sami Fares, Henry Stitzel, David Garib, Bassam Estfan, Suneel Kamath, Smitha Krishnamurthi, Wen Wee Ma, Teodora Kuzmanovic, Elizabeth Azzato, Emrullah Yilmaz, Jamak Modaresi Esfeh, Maureen Whitsett Linganna, Mazhar Khalil, Alejandro Pita, Andrea Schlegel, Jaekeun Kim, R. Matthew Walsh, Charles Miller, Koji Hashimoto, David Choon Hyuck Kwon, Federico Aucejo
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
liver transplant
circulating tumor DNA
liquid biopsy
liver cancer
hepatocellular carcinoma
cholangiocarcinoma
Online Access:https://www.mdpi.com/2072-6694/16/5/927

Internet

https://www.mdpi.com/2072-6694/16/5/927

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