Endothelial STING controls T cell transmigration in an IFNI-dependent manner

Endothelial STING controls T cell transmigration in an IFNI-dependent manner

The stimulator of IFN genes (STING) protein senses cyclic dinucleotides released in response to double-stranded DNA and functions as an adaptor molecule for type I IFN (IFNI) signaling by activating IFNI-stimulated genes (ISG). We found impaired T cell infiltration into the peritoneum in response to...

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Bibliographic Details
Main Authors: Marina Anastasiou, Gail A. Newton, Kuljeet Kaur, Francisco J. Carrillo-Salinas, Sasha A. Smolgovsky, Abraham L. Bayer, Vladimir Ilyukha, Shruti Sharma, Alexander Poltorak, Francis W. Luscinskas, Pilar Alcaide
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-08-01
Series:JCI Insight
Subjects:
Inflammation
Vascular biology
Online Access:https://doi.org/10.1172/jci.insight.149346

Internet

https://doi.org/10.1172/jci.insight.149346

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