Akkermansia muciniphila and its membrane protein ameliorates intestinal inflammatory stress and promotes epithelial wound healing via CREBH and miR-143/145

Akkermansia muciniphila and its membrane protein ameliorates intestinal inflammatory stress and promotes epithelial wound healing via CREBH and miR-143/145

Abstract Background The intestinal epithelial barrier is the interface for interaction between gut microbiota and host metabolic systems. Akkermansia muciniphila (A. muciniphila) is a key player in the colonic microbiota that resides in the mucus layer, whose abundance is selectively decreased in th...

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Bibliographic Details
Main Authors: Henry Wade, Kaichao Pan, Qihua Duan, Szczepan Kaluzny, Ekta Pandey, Linda Fatumoju, Viswanathan Saraswathi, Rongxue Wu, Edward N. Harris, Qiaozhu Su
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Biomedical Science
Subjects:
Akkermansia muciniphila
Amuc_1100
CREBH
microRNA-143/145
Intestinal inflammatory stress
Epithelial regeneration
Online Access:https://doi.org/10.1186/s12929-023-00935-1

Internet

https://doi.org/10.1186/s12929-023-00935-1

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