Functional Expression of Prestin, the Outer Hair Cell Motor Protein, Using the Baculovirus/Insect Cell System

Functional Expression of Prestin, the Outer Hair Cell Motor Protein, Using the Baculovirus/Insect Cell System

A source of the electromotility of the outer hair cells (OHCs), which enables the high sensitivity of mammalian hearing, is believed to be voltage-dependent conformational change of the motor protein prestin embedded in the lateral wall of the OHCs. As a result of extensive studies on this unique mo...

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Bibliographic Details
Main Authors: Takashi TADENUMA, Koji IIDA, Michio MURAKOSHI, Shun KUMANO, Kouhei TSUMOTO, Katsuhisa IKEDA, Toshimitsu KOBAYASHI, Izumi KUMAGAI, Hiroshi WADA
Format: Article
Language:English
Published: The Japan Society of Mechanical Engineers 2008-09-01
Series:Journal of Biomechanical Science and Engineering
Subjects:
outer hair cell
prestin
membrane protein expression
baculovirus
sf9 insect cell
patch-clamp technique
nonlinear capacitance
western blotting
Online Access:https://www.jstage.jst.go.jp/article/jbse/3/2/3_2_287/_pdf/-char/en

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https://www.jstage.jst.go.jp/article/jbse/3/2/3_2_287/_pdf/-char/en

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