Silencing of Unintegrated Retroviral DNAs

Retroviral infection delivers an RNA genome into the cytoplasm that serves as the template for the synthesis of a linear double-stranded DNA copy by the viral reverse transcriptase. Within the nucleus this linear DNA gives rise to extrachromosomal circular forms, and in a key step of the life cycle...

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Bibliographic Details
Main Author: Stephen P. Goff
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/11/2248