Silencing of Unintegrated Retroviral DNAs
Retroviral infection delivers an RNA genome into the cytoplasm that serves as the template for the synthesis of a linear double-stranded DNA copy by the viral reverse transcriptase. Within the nucleus this linear DNA gives rise to extrachromosomal circular forms, and in a key step of the life cycle...
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Format: | Article |
Language: | English |
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MDPI AG
2021-11-01
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Series: | Viruses |
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Online Access: | https://www.mdpi.com/1999-4915/13/11/2248 |