Guidance on the use of the benchmark dose approach in risk assessment

Guidance on the use of the benchmark dose approach in risk assessment

Abstract The Scientific Committee (SC) reconfirms that the benchmark dose (BMD) approach is a scientifically more advanced method compared to the no‐observed‐adverse‐effect‐level (NOAEL) approach for deriving a Reference Point (RP). The major change compared to the previous Guidance (EFSA SC, 2017)...

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Bibliographic Details
Main Authors: EFSA Scientific Committee, Simon John More, Vasileios Bampidis, Diane Benford, Claude Bragard, Thorhallur Ingi Halldorsson, Antonio F Hernández‐Jerez, Susanne Hougaard Bennekou, Kostas Koutsoumanis, Claude Lambré, Kyriaki Machera, Wim Mennes, Ewen Mullins, Søren Saxmose Nielsen, Dieter Schrenk, Dominique Turck, Maged Younes, Marc Aerts, Lutz Edler, Salomon Sand, Matthew Wright, Marco Binaglia, Bernard Bottex, Jose Cortiñas Abrahantes, Josef Schlatter
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:EFSA Journal
Subjects:
BMD
BMDL
benchmark response
NOAEL
dose–response modelling
BMD software
Online Access:https://doi.org/10.2903/j.efsa.2022.7584

Internet

https://doi.org/10.2903/j.efsa.2022.7584

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