Rectifying disorder of extracellular matrix to suppress urethral stricture by protein nanofilm-controlled drug delivery from urinary catheter

Abstract Urethral stricture secondary to urethral injury, afflicting both patients and urologists, is initiated by excessive deposition of extracellular matrix in the submucosal and periurethral tissues. Although various anti-fibrotic drugs have been applied to urethral stricture by irrigation or su...

Full description

Bibliographic Details
Main Authors: Juanhua Tian, Delai Fu, Yongchun Liu, Yibing Guan, Shuting Miao, Yuquan Xue, Ke Chen, Shanlong Huang, Yanfeng Zhang, Li Xue, Tie Chong, Peng Yang
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38282-2