Interplay between Thyroid Hormones and Stearoyl-CoA Desaturase 1 in the Regulation of Lipid Metabolism in the Heart

Interplay between Thyroid Hormones and Stearoyl-CoA Desaturase 1 in the Regulation of Lipid Metabolism in the Heart

Stearoyl-CoA desaturase 1 (SCD1), an enzyme that is involved in the biosynthesis of monounsaturated fatty acids, induces the reprogramming of cardiomyocyte metabolism. Thyroid hormones (THs) activate both lipolysis and lipogenesis. Many genes that are involved in lipid metabolism, including <i>...

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Bibliographic Details
Main Authors: Adam Olichwier, Volodymyr V. Balatskyi, Marcin Wolosiewicz, James M. Ntambi, Pawel Dobrzyn
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
SCD1
lipogenesis
lipolysis
β-oxidation
hypothyroidism
inflammation
Online Access:https://www.mdpi.com/1422-0067/22/1/109

Internet

https://www.mdpi.com/1422-0067/22/1/109

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