Maturation-Dependent Differences in the Re-innervation of the Denervated Dentate Gyrus by Sprouting Associational and Commissural Mossy Cell Axons in Organotypic Tissue Cultures of Entorhinal Cortex and Hippocampus

Sprouting of surviving axons is one of the major reorganization mechanisms of the injured brain contributing to a partial restoration of function. Of note, sprouting is maturation as well as age-dependent and strong in juvenile brains, moderate in adult and weak in aged brains. We have established a...

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Bibliographic Details
Main Authors: Mandy H. Paul, Lars Hildebrandt-Einfeldt, Viktor J. Beeg Moreno, Domenico Del Turco, Thomas Deller
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Neuroanatomy
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Online Access:https://www.frontiersin.org/articles/10.3389/fnana.2021.682383/full